An essay on human heart transplantation

The potency of therapy is dose dependent. The only therapy available for allograft vascular disease is retransplantation. A large multicenter cohort study found that pre transplant hepatitis C positivity was associated with decreased survival at a mean follow-up of 5.

Because of the short preservation time tolerated by the heart hoursprocurement distances are limited. The following paper discusses various psychiatric aspects of organ transplantation in general.

Heart Transplant

The patient is regularly monitored to detect rejection. The cause of the process is unclear. Renal-dose dopamine is no longer used routinely for all patients, as many studies have questioned its value.

Transplant recipients are maintained on an immunosuppression regimen that includes drugs. Of the four groups that he identified, namely, a the adjusted, b the symbiotic, c the depressed, and d those denying anxiety, it was the members of the latter two groups who caused further concern for the mental-health professionals.

Management of the patient usually includes monitoring intra-arterial blood pressure, central venous pressure CVPleft atrial pressure LAP and pulmonary artery pressures PAP. Before the advent of cyclosporine, overall results of heart transplant were not very good.

From the development of more powerful and specific immunosuppressants to new treatments for accelerated graft atherosclerosis, advances in the science of immunology appear to hold the key to expanding the success of heart transplantation in our treatment of end-stage cardiac disease. Organ rejection Rejection following cardiac transplant is most common in the first six to 12 weeks, although it can occur at any time.

Perform biopsies of appropriate areas if the patient exhibits symptoms of systemic disease. Currently, there is a trend toward reverting to bicaval anastomoses rather than right atrial anastomoses in an attempt to decrease the incidence of postoperative tricuspid insufficiency.

It may decrease proliferation of immune cells, which results in lower autoimmune activity. It is also is set to cool down the blood during the operation in order to protect the other organs. Another mythological creature depicted as a recumbent feline with a human head is the Greek Sphinx.

Maintain vigilance for other uncommon infectious processes, including Listeria, Legionella, Chlamydia, and Nocardia infection. InColumbia University Medical Center became one of a small group of medical centers to initiate clinical trials of cyclosporine, which was approved for commercial use in November of that year, and is still today the most commonly prescribed immunosuppressant used in organ transplantation.

Hire Writer The limitations of a donor heart transplant are that the patients might suffer from other circulatory conditions unrelated to the heart. In the transplantation process, the sinoatrial nodes of the donor and recipient remain intact, and both are present within the recipient.

This first clinical heart transplantation experience stimulated world-wide notoriety, and many surgeons quickly co-opted the procedure. The surgery takes about five hours. However, because many patients were dying soon after, the number of heart transplants dropped from into just 18 in The first heart transplant in human beings was done in South Africa in by Dr.

Several regimens can be used, including pre transplantation induction therapy and simple postoperative maintenance therapy; the choice of regimen depends on the training and experience of the transplantation center.

Complications Post-operative complications include infection, sepsis, organ rejection, as well as the side-effects of the immunosuppressive medication. Life-threatening arrhythmias are rare postoperatively, even during acute rejection episodes.

Precise fluid management will help prevent pulmonary oedema. Posteroanterior and lateral chest radiographs are used to screen for other thoracic pathologies that may preclude transplantation. Biopsy Endomyocardial biopsy of the potential candidate is not routinely performed.

Introduction to heart transplant The idea of replacing a bad organ with a good one has been documented in ancient mythology. Neoral is the capsular form of cyclosporine, available in and mg capsules.

Sirolimus Rapamune Sirolimus, also known as rapamycin, is a macrocyclic lactone produced by Streptomyces hygroscopicus. Methylprednisolone Medrol, Solu-Medrol, A-Methapred Methylprednisolone is an immunosuppressant used to treat autoimmune disorders.

Medication The goals of pharmacotherapy are to prevent complications, to reduce morbidity, and to reduce the chances for organ rejection.

Triple therapy anti-rejection treatment consisting of cyclosporin, azathioprine and prednisolone is most commonly administered postoperatively, but the drug regimen will vary from centre to centre.

Cardiac Transplant Program

At the same time, the heart is removed from the donor and inspected by a team of surgeons to see if it is in suitable condition. These suture lines connect the large blood vessels entering and leaving the heart. Regular monitoring of urea and electrolyte levels, maintenance of optimal fluid balance and avoidance of unnecessary nephrotoxic drugs will help.

Fungal infections can appear if the patient is diabetic or excessively immunosuppressed. Does the patient need a donor council. Various organs and animal tissues were kept alive for many years in this fashion.

Heart Transplant Essay Sample

The first heart transplant in human beings was done in South Africa in by Dr. Christiaan Barnard; the patient only lived 18 days. Most of the research that led to successful heart transplantation took place in the United States at Stanford University under the leadership of Dr.

Norman Shumway. Once Stanford started reporting better results. Heart Transplant Essay Sample. Cardiac transplantation, also called heart transplantation, has evolved into the treatment of choice for many people with severe heart failure (HF) who have severe symptoms despite maximum medical therapy.

What is a Heart Transplant? Essay. Length: words (4 double-spaced pages) Rating: Better Essays. Cardiac surgeons will only perform heart transplantation, if only congestive heart failure was diagnosed in the patient.

It is predicted that cardiac xenotransplantation may.

Heart Transplant Essay Sample

This first clinical heart transplantation experience stimulated world-wide notoriety, and many surgeons quickly co-opted the procedure. However, because many patients were dying soon after, the number of heart transplants dropped from into just 18 in Whether a patient needs a new kidney, liver, heart, or lung, there are multiple issues that the patient and the family need to deal with.

They involve decisions before. Heart transplant is a transplant procedure surgery where the malfunctioning heart or end-stage heart-related disease are replaced by a function heart.

Indeed, this is a very complicated, risky and time-consuming operation since it needs a function heart from the person who has just died and implant.

An essay on human heart transplantation
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Heart Transplant – Assignment Example